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Carolina González-Cavazos is a PhD student mentored by Professor Andrew Su. Before joining Su Lab, she was a research intern at Caltech, focusing on autism spectrum disorder genetic variants. She completed her undergraduate studies in genomics at Universidad Autonoma de Nuevo Leon, Mexico. Currently, her thesis focuses on implementing graph neural network (GNN) explainability models in biomedical knowledge graphs. Carolina’s research aims to provide interpretable explanations that support the discovery of novel drug-disease associations.

Publications

2026

A Case-Based Explainable Graph Neural Network Framework for Mechanistic Drug Repositioning
Adriana Carolina Gonzalez-Cavazos, Roger Tu, Meghamala Sinha, Andrew I Su
Bioinformatics  ·  14 Jan 2026  ·  doi:10.1093/bioinformatics/btag008  ·  PMID: 41533699

2023

DrugMechDB: A Curated Database of Drug Mechanisms
Adriana Carolina Gonzalez-Cavazos, Anna Tanska, Michael Mayers, Denise Carvalho-Silva, Brindha Sridharan, Patrick A. Rewers, Umasri Sankarlal, Lakshmanan Jagannathan, Andrew I. Su
Scientific Data  ·  16 Sep 2023  ·  doi:10.1038/s41597-023-02534-z  ·  PMID: 37717042  ·  PMCID: PMC10505144
Drug Repurposing using consilience of Knowledge Graph Completion methods
Roger Tu, Meghamala Sinha, Carolina González, Eric Hu, Shehzaad Dhuliawala, Andrew McCallum, Andrew I. Su
openRxiv  ·  14 May 2023  ·  doi:10.1101/2023.05.12.540594  ·  PMID: 39149283  ·  PMCID: PMC11326126
DrugMechDB: A Curated Database of Drug Mechanisms
Adriana Carolina Gonzalez-Cavazos, Anna Tanska, Michael D. Mayers, Denise Carvalho-Silva, Brindha Sridharan, Patrik A. Rewers, Umasri Sankarlal, Lakshmanan Jagannathan, Andrew I. Su
openRxiv  ·  02 May 2023  ·  doi:10.1101/2023.05.01.538993  ·  PMID: 37205439  ·  PMCID: PMC10187194

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