Distribution of GO annotations among human genes

Recently, someone emailed me to ask how I got the data behind this figure that I often use in the introductions of my talks: This figure shows that while there are few genes that are very well annotated (100s of GO annotations manually annotated by biocurators), that degree of annotation falls off very quickly. At the time I last did the analysis, 65% of genes had 5 or fewer GO annotations, and...
read more

Sequenced genomes per year

As part of building the case for creating our proposed CMOD resource, we wanted to know just how quickly the number of sequenced genomes was increasing. The thinking is that the more genomes are being sequenced, the more genomes there are that are going with virtually no community bioinformatics support. write college essays for money There are two sources of release dates for sequenced genomes...
read more

The Centralized Model Organism Database

This guest post was written by Adriel Carolino, a summer intern who has been spearheading this project to create a Centralized Model Organism Database (CMOD). The recent explosion of metagenomic sequencing has resulted in an immense expanse of microbial genetic information.  Current metagenomic analyses typically revolve around a taxonomic survey — describing what microbial species are...
read more

Twenty questions for genes — try it out

Part 1: Introduction to the concept Part 2: The prototype game (this post) Part 3: Evaluation framework We recently posted on this blog the idea of creating a computer engine to play the game 20 questions. But instead of asking users to thing of common objects in the world, we’d ask people to think of their favorite gene. Well, I took advantage of a recent long weekend to throw together a...
read more

Twenty questions for genes

Part 1: Introduction to the concept (this post) Part 2: The prototype game Part 3: Evaluation framework If I asked you to think of your favorite gene, do you think I could guess the identity of that gene by first asking you twenty yes / no questions? I personally might not be a very good guesser in this game, but I’m betting that we can write a computer program that would be pretty...
read more

Gene Wiki update paper

Our second paper on the Gene Wiki ijkey=70heWcVDzEvSzl5&keytype;=ref “>was published online today in the journal Nucleic Acids Research. It will also be included in the 2010 Database issue in January. From the concluding paragraph of the introduction: Here, we present an update describing the recent systematic improvements to the Gene Wiki. Moreover, we report on a retrospective analysis...
read more