Kerin Higa



Hope for Huntington’s Disease—#GeneOTW with HTT

Huntington’s Disease (HD) is a devastating neurodegenerative disorder that affects approximately one in every 20,000 Americans.  HD’s namesake, George Huntingon, was not the first but the most acclaimed reporter of the disease.  In 1872, when he was just 22 years old (!), he published his paper “On chorea,” in which he described the clinical features of the disease.1 Symptoms of HD include...
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I need some AIRE — #GeneOTW

If you’ve been reading my Gene-of-the-Week posts for a while, you may recall that, although I know admittedly little about the immune system, I have a particular, personal interest in autoimmune diseases.  Recently, my immune system has been aberrantly attacking my own healthy tissues, resulting in some really annoying joint pain and swelling.  As much as it sucks, the more I learn about...
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PGM1 Deficiency: Best New Disease of 2014?— #GeneOTW

2014 is almost over, my friends. The year is coming to a close, and like every year—but probably plenty more this year, thanks to Buzzfeed—a barrage of “Best of” lists will soon besiege us. Already, we have had the best subreddits, the best movie posters, and the best wine books of 2014 enumerated for us. But what I am really looking forward to this year is the Best Newly Discovered Diseases of...
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Be Thankful for the Little Things… — #GeneOTW with DICER1

Be Thankful for the Little Things… and the big things that make the little things work  I’ve said it before: small things can make a big difference.  This Thanksgiving (and every day), it’s important that we remember and give thanks for the little things.  The little things, like microRNAs (miRNAs). miRNAs are small, non-coding RNAs that are important for the inhibition of gene...
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I regret eating my placenta — #GeneOTW with PLAC1

Just kidding, guys.  I haven’t had a baby.  And even if I had, I doubt I would have eaten the placenta.  But I just couldn’t resist stealing the title of this NY Times blog post that happens to be the third result when I googled “placenta.” Why was I googling “placenta”?  Not for the pictures, that’s for sure!   I googled “placenta” to...
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