It’s been an interesting year for BioGPS. Looking back at 2015, the BioGPS paper was cited 754 times according to google scholar. Of those citations, 137 were in 2015. The BioGPS application paper about BioGPS and MyGene.info from 2013 was cited 40 times this year for a total of 96 citations. An update on BioGPS was accepted for publication last year and should appear in this year’s database issue of Nucleic Acids Research.
BioGPS had a major overhaul in June, with thousands of additional datasets added from Array Express, which allowed the user to customize the gene expression charts based of factors of interest. Additionally, charts from datasets with multiple samples could now be viewed with the individual samples collapsed together with an error bar.
BioGPS logging was down during parts of July and August, hence the actual number of queries made last year is not available. Using the remaining 10 months to estimate the average monthly queries and then projecting that average to 12 months, BioGPS received an estimated 1,060,944 queries last year—up from 972,401 queries in 2014.
Aside from CDK2 (the default gene searched), the top five most queried genes of 2015 were genes 7157 (TP53), 1956 (EGFR), 60 (ACTB), 2597 (GAPDH), and 2064 (HER2). Of these top queried genes, only 2597 (GAPDH), and 2064 (ERBB2) had changed ranks since 2014. Additionally, three papers citing BioGPS in 2015 were found in a pubmed search about Epidermal Growth Factor (EGF):
- Epidermal growth factor, latrophilin, and seven transmembrane domain-containing protein 1 marker, a novel angiogenesis marker
- Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions
- Genetic variants modulating CRIPTO serum levels identified by genome-wide association study in Cilento isolates
For those of you that used BioGPS, created a plugin, contacted us about a bug, shared or tweeted about BioGPS, or made a suggestion… THANK YOU! If you’ve published a paper citing BioGPS and would like to share more about your research, we’d love to feature your work on our blog, so please get in touch! We look forward to hearing from you in 2016.