Mark2Cure is a citizen science tool that empowers anyone who can read to make biomedical research literature more useful for researchers. Mark2Cure citizen scientists improve their ability to read and understand biomedical research abstracts while enabling researchers to more efficiently utilize biomedical research literature. Ultimately, Mark2Cure aims to annotate all biomedical research literature since certain diseases may be related to other diseases in unexpected ways. However, every ambitious project needs an attainable starting goal. For Mark2Cure, this goal is annotating rare genetic disease research literature. Historically, rare genetic disease researchers have relied heavily on patient communities and foundations to fund their work. Many of the discoveries on rare genetic diseases would not be possible without the highly active and extremely dedicated community of patients/parents of patients. Mark2Cure invites members of these communities to help researchers spend less time studying research literature, and more time finding a cure.